In Zollino there is a station of the FSE (railways of the South-East), which is about 1 km from Palazzo Mandurino, where only regional trains arrive, for the national and international trains the nearest station is in Lecce.
Zollino is located 15 km south of Lecce; to reach Palazzo Mandurino you need to take the SS16 towards Maglie Santa Maria di Leuca, and take the Soleto Sud exit. For those arriving by plane, the nearest airport is Brindisi Casale, which is 60 km away (along the SS613).
The nearest port is located in Otranto, 29 km from Zollino (via SS16).
Zollino is located in a central strategic position from the point of view of the seaside towns, since travelling a few kilometers you can reach Otranto, Gallipoli and Torre dell'Orso.